Na+/K+-ATPase alpha1 Polyclonal AntibodyE-AB-12562
Product Type: Antibody
Descritpion: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Areas: Cancer, Metabolism, Neuroscience, Signal transduction, Tags & Cell Markers
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_000692
Immunogen: Synthetic peptide of human ATP1A1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control:
Cellular Localization: Cell membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-na+_k+_atpase_alpha1_polyclonal_antibody-32007.html
Manual Link: https://www.elabscience.com/viewpdf-32007-elabscience-E-AB-12562.PDF