S100A1 Polyclonal AntibodyE-AB-12634
Product Type: Antibody
Descritpion: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
Research Areas: Cancer, Neuroscience, Signal transduction, Tags & Cell Markers
Recommended Dilutions: IHC 1:50-1:100
Size: 200 uL
Gene Accession: NP_006262
Immunogen: Synthetic peptide of human S100A1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain.
Cellular Localization: Cytoplasm.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-s100a1_polyclonal_antibody-32078.html
Manual Link: https://www.elabscience.com/viewpdf-32078-elabscience-E-AB-12634.PDF