Product Type: Antibody
Descritpion: IGSF4C (immunoglobulin superfamily member 4C), also known as CADM4 (cell adhesion molecule 4), NECL4 or TSLL2, is a 388 amino acid single-pass type I membrane protein that contains one Ig-like V-type domain and two Ig-like C2-type domains. Expressed in kidney, brain and prostate, IGSF4C exists as both a monomer and a homodimer and is thought to be involved in cell-cell adhesion, possibly playing a role in tumor suppression. Human IGSF4C shares 98% sequence identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding IGSF4C maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs)
Research Areas: Cancer
Recommended Dilutions: WB 1:200-1:1000, IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_660339
Immunogen: Synthetic peptide of human CADM4
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 43kDa
Tissue Specificity/Positive Control: Expressed in brain, prostate, brain, kidney and some other organs.
Cellular Localization: Membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-cadm4_polyclonal_antibody-32544.html
Manual Link: https://www.elabscience.com/viewpdf-32544-elabscience-E-AB-13104.PDF