Product Type: Antibody
Descritpion: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: NP_005185
Immunogen: Synthetic peptide of human CEBPB
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Expressed at low levels in the lung, kidney and spleen.
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-cebp_beta_polyclonal_antibody-32583.html
Manual Link: https://www.elabscience.com/viewpdf-32583-elabscience-E-AB-13143.PDF