Product Type: Antibody
Descritpion: Cell adhesion molecule 3 is a protein that in humans is encoded by the CADM3 gene. IGSF4B is a brain-specific protein related to the calcium-independent cell-cell adhesion molecules known as nectins. Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions.
Research Areas: Neuroscience
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC033819
Immunogen: Recombinant protein of human CADM3
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Isoform 1 is expressed mainly in adult and fetal brain. Isoform 2 is highly expressed in adult brain and weakly expressed in placenta. In brain, Isoform 2 is highly expressed in cerebellum.
Cellular Localization: Cell junction. Cell membrane. Localized at the cell-cell attached sites of the plasma membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.