Anti-Human CD45RA Monoclonal Antibody (PerCP/Cy5.5 Conjugated)E-AB-1690
Product Type: monoclonal antibody for FC
Description: CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naive T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.
Resarch Areas: Immunology, Stem cells
Clone No: HI100
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used from 20 µL to 5 µL per 100 µL of peripheral blood or 10^6 cells in 100 µl. Please check your vial). Since applications vary, the appropriate dilutions must be determined for individual use.
Isotype: Mouse IgG2a
Formulation: PBS with 0.09% NaN3, 0.2% BSA, PH7.2
Storage: Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.
Product Link: https://www.elabscience.com/p-anti_human_cd45ra_monoclonal_antibody_(percp_cy5.5_conjugated)-39174.html
Manual Link: https://www.elabscience.com/viewpdf-39174-elabscience-E-AB-1690.PDF