LEP Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction, Stem cells
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:30-150, ELISA 1:2000-10000
Size: 200 uL
Concentration: 0.5mg/mL
Swissprot: Q6NT58
Gene Accession: BC069323
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Full length fusion protein
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control:
Cellular Localization: Extracellular region or secreted,extracellular region
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-lep_polyclonal_antibody-36382.html
Manual Link: https://www.elabscience.com/viewpdf-36382-elabscience-E-AB-16987.PDF