Anti-Mouse CD40 Monoclonal Antibody (Biotin conjugated)E-AB-2076
Product Type: monoclonal antibody for FC
Description: CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154(gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
Resarch Areas: Cancer, Cardiovascular, Immunology, Stem cells
Size: 500 ug
Clone No: FGK4.5
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used ? 1.0 µg/10^6 cells in 100 µl). Since applications vary, the appropriate dilutions must be determined for individual use.
Isotype: Rat IgG2a
Formulation: PBS with 0.09% NaN3, 0.2% BSA, PH7.2
Storage: Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.
Product Link: https://www.elabscience.com/p-anti_mouse_cd40_monoclonal_antibody_(biotin_conjugated)-39327.html
Manual Link: https://www.elabscience.com/viewpdf-39327-elabscience-E-AB-2076.PDF