Phospho-LIMK1 (Thr508) Polyclonal Antibody

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal transduction
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,IHC-p,IF,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Clonality: Polyclonal
Clone No:
SwissProt: P53667
Gene ID: 3984
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human LIMK-1 around the phosphorylation site of Thr508
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 72kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cytoplasm. Cell projection>growth cone.

Product Link: https://www.elabscience.com/p-phospho_limk1_(thr508)_polyclonal_antibody-25507.html
Manaul Link: https://www.elabscience.com/viewpdf-25507-elabscience-E-AB-20918.PDF