Phospho-BCL2 (Ser70) Polyclonal Antibody

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Research Areas: Cancer, Cell Biology, Metabolism, Signal transduction
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,ELISA
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:40000
Clonality: Polyclonal
Clone No:
SwissProt: P10415
Gene ID: 596
Reactivity: Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human Bcl-2 around the phosphorylation site of S70.
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 26kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Mitochondrion outer membrane. Nucleus membrane. Endoplasmic reticulum membrane.

Product Link: https://www.elabscience.com/p-phospho_bcl2_(ser70)_polyclonal_antibody-25672.html
Manaul Link: https://www.elabscience.com/viewpdf-25672-elabscience-E-AB-21083.PDF