Phospho-CXCR4 (Ser339) Polyclonal Antibody

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. 
Research Areas: Cancer, Metabolism, Immunology, Microbiology, Neuroscience, Stem cells
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,IHC-p,IF,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Clonality: Polyclonal
Clone No:
SwissProt: P61073
Gene ID: 7852
Reactivity: Human,Mouse,Rat,Monkey
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human Fusin around the phosphorylation site of Ser339
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 38kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cell membrane. In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated.

Product Link: https://www.elabscience.com/p-phospho_cxcr4_(ser339)_polyclonal_antibody-25871.html
Manaul Link: https://www.elabscience.com/viewpdf-25871-elabscience-E-AB-21282.PDF