Phospho-HDAC6 (Ser22) Polyclonal Antibody

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Stem cells
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,IHC-p,IF,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Clonality: Polyclonal
Clone No:
SwissProt: Q9UBN7
Gene ID: 10013
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human HDAC6 around the phosphorylation site of Ser22
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 131kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Nucleus. Cytoplasm. It is mainly cytoplasmic, where it is associated with microtubules.

Product Link: https://www.elabscience.com/p-phospho_hdac6_(ser22)_polyclonal_antibody-25875.html
Manaul Link: https://www.elabscience.com/viewpdf-25875-elabscience-E-AB-21286.PDF