Product Type: Antibody
Descritpion: Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Research Areas: Cancer, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300 ELISA 1:20000
Size: 200 uL
Immunogen: Synthesized peptide derived from the C-terminal region of human Cytokeratin 19.
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Tissue Specificity/Positive Control: Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.
Cellular Localization: Cytoplasm
Storage: Store at -20C. Avoid freeze / thaw cycles.