AKAP14 Polyclonal AntibodyE-AB-30454
Product Type: Antibody
Descritpion: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The protein anchors PKA in ciliary axonemes and, in this way, may play a role in regulating ciliary beat frequency. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.AKAP14 (A-Kinase Anchoring Protein 14) is a Protein Coding gene. GO annotations related to this gene include protein kinase A binding.
Research Areas: Cancer, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Size: 200 uL
Immunogen: Synthesized peptide derived from the N-terminal region of human AKAP 14
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 23kDa
Tissue Specificity/Positive Control: Present in cilia (at protein level). Expressed in tissues containing axoneme-based organelles (cilia and/or flagella): trachea and testis. Highly expressed in airway cilia.
Cellular Localization: Cytoplasmic
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-akap14_polyclonal_antibody-26779.html
Manual Link: https://www.elabscience.com/viewpdf-26779-elabscience-E-AB-30454.PDF