PAX2 Polyclonal AntibodyE-AB-32509
Product Type: Antibody
Descritpion: PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Neuroscience
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human Pax-2.
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 45kDa
Tissue Specificity/Positive Control: Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.
Cellular Localization: Nuclear
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-pax2_polyclonal_antibody-28834.html
Manual Link: https://www.elabscience.com/viewpdf-28834-elabscience-E-AB-32509.PDF