ARHGEF11 Polyclonal AntibodyE-AB-32540
Product Type: Antibody
Descritpion: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.
Research Areas: Signal transduction
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:5000
Size: 200 uL
Immunogen: Synthesized peptide derived from the N-terminal region of human PDZ-RhoGEF
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 168kDa
Tissue Specificity/Positive Control: Ubiquitously expressed.
Cellular Localization: Cytoplasm. Membrane. Translocated to the membrane upon stimulation.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-arhgef11_polyclonal_antibody-28865.html
Manual Link: https://www.elabscience.com/viewpdf-28865-elabscience-E-AB-32540.PDF