PLCG1 Polyclonal AntibodyE-AB-32623
Product Type: Antibody
Descritpion: Plays a role in actin reorganization and cell migration. The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.
Research Areas: Cancer, Cardiovascular, Metabolism, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from human PLC ?1 around the non-phosphorylation site of Tyr771.
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 149kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cell projection>lamellipodium. Cell projection>ruffle. Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-plcg1_polyclonal_antibody-28948.html
Manual Link: https://www.elabscience.com/viewpdf-28948-elabscience-E-AB-32623.PDF