PMS2 Polyclonal AntibodyE-AB-32630
Product Type: Antibody
Descritpion: This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human PMS2
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Calculated MW: 96kDa
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-pms2_polyclonal_antibody-28955.html
Manual Link: https://www.elabscience.com/viewpdf-28955-elabscience-E-AB-32630.PDF