PPP2R1B Polyclonal AntibodyE-AB-32639
Product Type: Antibody
Descritpion: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
Research Areas: Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ICC 1:200-1:1000, ELISA 1:40000
Size: 200 uL
Immunogen: Synthesized peptide derived from the C-terminal region of human PP2A-A?
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 66kDa
Tissue Specificity/Positive Control:
Cellular Localization: Extracellular region or secreted,extracellular exosome,Other locations:membrane raft
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-ppp2r1b_polyclonal_antibody-28964.html
Manual Link: https://www.elabscience.com/viewpdf-28964-elabscience-E-AB-32639.PDF