RPL28 Polyclonal AntibodyE-AB-32798
Product Type: Antibody
Descritpion: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L28E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.RPL28 (Ribosomal Protein L28) is a Protein Coding gene. Diseases associated with RPL28 include Albinism-Deafness Syndrome. Among its related pathways are Viral mRNA Translation and rRNA processing in the nucleus and cytosol. GO annotations related to this gene include poly(A) RNA binding and structural constituent of ribosome.
Research Areas: Epigenetics and Nuclear Signaling
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Size: 200 uL
Immunogen: Synthesized peptide derived from the Internal region of human Ribosomal Protein L28
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Calculated MW: 16kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytosolic large ribosomal subunit,Extracellular region or secreted,extracellular exosome,Other locations:cell body,cytoplasmic ribonucleoprotein granule,dendrite,membrane
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-rpl28_polyclonal_antibody-29123.html
Manual Link: https://www.elabscience.com/viewpdf-29123-elabscience-E-AB-32798.PDF