DNAL1 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry (PubMed:21496787).
Research Areas: Signal transduction
Applications: IHC
Recommended Dilutions: IHC 1:50-1:100
Size: 200 uL
Concentration: 2mg/mL
Swissprot: Q4LDG9
Gene Accession:
Reactivity: Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant Dynein light chain 1, axonemal protein
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Expressed in tissues carrying motile cilia such as testis.
Cellular Localization: Cytoskeleton,microtubule,outer dynein arm
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-dnal1_polyclonal_antibody-26257.html
Manual Link: https://www.elabscience.com/viewpdf-26257-elabscience-E-AB-40076.PDF