MMP1 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Research Areas: Cancer, Cell Biology, Cardiovascular, Signal transduction
Applications: IHC
Recommended Dilutions: IHC 1:50-1:100
Size: 200 uL
Concentration: 2mg/mL
Swissprot: P03956
Gene Accession:
Reactivity: Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant human Matrix metalloprotease 1 protein
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control:
Cellular Localization: Secreted>extracellular space>extracellular matrix.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-mmp1_polyclonal_antibody-40698.html
Manual Link: https://www.elabscience.com/viewpdf-40698-elabscience-E-AB-40152.PDF